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For more information call (909) 865-9555. |
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RTOG 0413 / NSABP B-39
Principal Investigator: Y.S. Ram Rao, M.D. A Randomized Phase III Study of Conventional Whole Breast Irradiation versus Partial Breast Irradiation for Women with Stage 0, I, or II Breast Cancer. The purpose of this study is to see if partial breast irradiation is as good as or better than whole breast irradiation in keeping cancer from coming back in the breast. |
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SWOG 0307
Principal Investigator: Y.S. Ram Rao, M.D. Phase III Trial of Bisphosphonates as Adjuvant Therapy for Primary Breast Cancer. This study is investigational and is being done to find out if adding a drug (a bisphosphonate) to hormonal therapy or chemotherapy will help prevent cancer from spreading to the bones or other parts of the body. |
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NSABP B-42
Principal Investigator: Y.S. Ram Rao, M.D. A Clinical Trial to Determine the Efficacy of Five Years of Letrozole Compared to Placebo in Patients Completing Five Years of Hormonal Therapy Consisting of an Aromatase Inhibitor (AI) or Tamoxifen Followed by an AI in Prolonging Disese-Free Survival in Postmenopausal Women with Hormone Receptor Positive Cancer. The main purpose of the study is to learn whether or not continuing hormonal therapy with an aromatase inhibitor (AI) called Letrozole for 5 additional years after already taking 5 years of hormonal therapy (which included an AI) can further reduce the chance of breast cancer returning. |
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PACCT-1
Principal Investigator: Y.S. Ram Rao, M.D. Program for the Assessment of Clinical Tests (PACCT-1) Trial Assigning Individualized Option for Treatment: The TAILORx Trial. |
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For more information call (909) 865-9555. |
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NSABP-R-04
Principal Investigator: Y.S. Ram Rao, M.D. A Clinical Trial Comparing Preoperative Radiation Therapy and Capecitabine with Preoperative Therapy and Continuous Intravenous Infusion (CVI) of 5-FU in the Treatment of Patients with Operable Carcinoma of the Rectum. |
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For more information call (909) 865-9555. |
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RTOG 0522
Principal Investigator: Y.S. Ram Rao, M.D. A Randomized Phase III Trial of Concurrent Accelerated Radiation and Cisplatin Versus Concurrent Accelerated Radiation, Cisplatin, and Cetuximab (C225)[Followed by Surgery for Selected Patients] for Stage III and IV Head and Neck Carcinomas. |
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For more information call (909) 865-9555. |
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SW0G 424
Principal Investigator: Y.S. Ram Rao, M.D. Molecular Epidemiology Case-Series Study of Non-Small Cell Lung Cancer in Smoking and Non-Smoking Women and Men. The purpose of this study is to determine why women are more likely to be diagnosed with certain types of lung cancer than men are, and to see if factors other than smoking may put women at higher risk of lung cancer than men. We also want to understand what factors are associated with lung cancer in men and women who do not smoke. |
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RTOG L0127
Principal Investigator: Y.S. Ram Rao, M.D. A Phase III Chemoprevention Trial of Selenium Supplementation in Persons with Resected Stage I Non-Small Cell Lung Cancer. |
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For more information call (909) 865-9555. |
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CALGB-90202
Principal Investigator: Y.S. Ram Rao, M.D. A Randomized, Double-Blind, Placebo-Controlled Phase III Study of Early versus Standard Zoledronic Acid to Prevent Skeletal Related Events in Men with Prostate Cancer Metastic to Bone. The purpose of this study is to compare the effects (good and bad) of early treatment with zoledronic acid (Zometa) compared to standard treatment with zoledronic acid. We know that treatment with zoledronic acid decreases the risk of certain skeletal (bone) related events in men with prostate cancer AFTER the cancer has spread to the bones and continues to grow even with hormonal therapy (standard treatment). This research is being done because we do not know whether earlier treatment with zoledronic acid (started BEFORE the cancer grows with hormonal therapy) is better or worse than standard treatment. |
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RTOG 0518
Principal Investigator: Y.S. Ram Rao, M.D. A Phase III, Double-Blind, Placebo-Controlled study to evaluate the efficacy of Zometa for the prevention of Osteoporosis and associated fractures in patients receiving radiation therapy and long term LHRH Agonists for high-grade and/or locally advanced Prostate Cancer. |
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For more information call (909) 865-9555. |
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RTOG 0433
Principal Investigator: Y.S. Ram Rao, M.D. A Phase III International Randomized Trial of Single Versus Multiple Fractions for Re-irradiation of Painful Bone Metastases. |
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RTOG 0517
Principal Investigator: Y.S. Ram Rao, M.D. Randomized Phase III Trial to Evaluate Radiopharmaceuticals and Zoledronic Acid in Osteoblastic Metastases from Lung, Breast and Prosate Cancer. The purpose of this study is to compare the effects, good and/or bad, of a two different combinations of drugs to see which is better. |
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INS-06-007
Principal Investigator: Y.S. Ram Rao, M.D. Open Label Multi-Center Safety Trial of Fentanyl Sublingual Spray (Fentanyl SL Spray) for the Treatment of Breakthrough Cancer Pain. |
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